Modeling Services

QSP modeling
Quantative Systems Pharmaology (QPS) modeling is the approach enables us to reconstruct the effects of taking medication in terms of clinically measured biomarkers and end-points, predict the efficacy of a drug in humans on the basis of data obtained in animals, search for optimal combinational therapies, and more.
PBPK/RO Modeling
Physiologically Based Pharmacokinetic (PBPK) and Receptor Occupancy
Mechanistic PK/PD Modeling
Pharmacokinetic/Pharmacodynamic (PK/PD) modeling
Computational environment for QSP modeling & simulations
InSysBio provides a suite of integrated computational tools to support the full lifecycle of QSP model development and simulation. These tools combine mechanistic modeling capabilities, data integration, and high-performance computing to enable efficient, reproducible, and scalable analyses.
Translational Modeling: From Animal to Human, From In Vitro to Clinic
Identification of FIH Dose & RP2D
Optimization of clinical study design
Prediction of Response to Combination Therapies
Prediction of Best-in-Class Properties
Comparison with Competitors
Therapeutic areas:
  • Oncology and immuno-oncology
  • Immunology & Inflammation
  • Neurodegenerative diseases
  • Rare diseases