Journal articles


Evgeny Metelkin. Heta compiler: a software tool for the development of large-scale QSP models and compilation into simulation formats. JOSS: The Journal of Open Source Software. 2021. 6(67), 3708. doi: 10.21105/joss.03708.

Bloomingdale P., Karelina T., Cirit M., Muldoon SF., Baker J., McCarty W.J, Geerts H., Macha S. Quantitative systems pharmacology in neuroscience: Novel methodologies and technologies. CPT: Pharmacometrics Syst Pharmacology. 2021. doi: 10.1002/psp4.12607.

Karelina T., Lerner S., Stepanov A., Meerson M., Demin O. Monoclonal antibody therapy efficacy can be boosted by combinations with other treatments: predictions using an integrated Alzheimer's Disease Platform. CPT Pharmacometrics Syst Pharmacology. 2021. doi: 10.1002/psp4.12628.


Borisov I., Metelkin E. Confidence intervals by constrained optimization—An algorithm and software package for practical identifiability analysis in systems biology. PLoS Comput Biol 16(12): e1008495.


Stepanov A., Karelina T., Markevich N., Demin O., Nicholas T. A mathematical model of multisite phosphorylation of tau protein. PLOS ONE 13(3): e0194002. doi: 10.1371/journal.pone.0192519.

Smirnov S., Demin O., Torgonskaya M., Firsova Yu., Zhukov V., Zagustina N. Optimization of the Process of Air Purification from Dichloromethane in a Biofilter with an Irrigated Layer by Mathematical Modeling. Appl Biochem Microbiol (2018) 54: 702.