June 2, 2021
Elena Vasileva, student of Lomonosov Moscow State University (MSU) has developed her diploma thesis in InSysBio and successfully passed its defense. Her diploma thesis entitled “Optimization of anti-CD47 therapeutic agent dosage using PK/PD modeling” was supervised by Oleg Demin Jr, Head of Oncology and Immuno-Oncology at InSysBio. It’s worth highlighting that Elena Vasileva and Oleg Demin Jr prepared the poster “Prediction of target receptor occupancy for ALX148, a CD47 blocker, using mechanistic PK/RO modeling” based on the diploma thesis and presented it in frames of AACR 2020 (American Association for Cancer Research Annual Meeting) and ACoP11! However, they are continuing to develop the subject with another poster presentation.
About InSysBio
InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 120 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com.
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18 Nov 2019 19:58
Course “Modeling for systems biology and biomedicine” at the Faculty of Bioengineering and Bioinformatics
This year InSysBio CEO Dr Oleg Demin with expert modelers Tatiana Karelina and Evgeny Metelkin and modelers Dmitry Shchelokov, Svetlana Rubina and Veronika Musatova are giving the course “Modeling for systems biology and biomedicine” at the Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University.
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25 Nov 2019 18:47
PK/RO simulator for anti-PD-1 mAbs
InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP), modeling and simulation for drug development, announced the launch of application ‘PK/RO simulator for anti-PD-1 mAbs’. The application is based on the model allowing to predict pharmacokinetics and target binding in human for therapeutic antibodies against PD-1 receptor.
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