December 23, 2021
CYTOCON DB and CYTOCON DB Open are updated!
CYTOCON DB is a database of human baseline concentrations of cytokines and cells measured in different tissues. CYTOCON DB Open is a version of the database designed for public use. It has the same functionality as CYTOCON DB, however, it is updated once per year.
In 2021 CYTOCON DB Open was extended with new data: 135 diseases, 109 tissues, 125 molecules, 43 cells and 22305 concentrations were introduced. For this purpose 476 articles were reviewed.
As for CYTOCON DB, its latest version 1.3.8.22 contains approximately 35000 concentrations and 1000 articles were reviewed for these purpose!
Recent update result - in unit %__T-cells_;CD8+_Blood_COVID-19 - average concentration of CD8+ T-cells was changed from 207933 to 214081 kcells/L (averaged from 135 concentrations from articles annotated to the DB)
In unit %__T-cells_;CD4+_Blood_COVID-19 - average concentration of CD4+ T-cells was changed from 345548 to 353710 kcells/L (averaged from 166 concentrations from articles annotated to the DB)
For more details, please visit: https://cytocon.insysbio.com/
To experience CYTOCON DB Open visit: https://www.cytocon-open.insysbio.com/
About InSysBio
InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com.
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03 Aug 2020 16:00
InSysBio to share new data in frames of its Open Source QSP model of COVID-19
InSysBio has received a new set of results in framework of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.
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06 Aug 2020 17:51
InSysBio to update its Cytocon DB and to present version 1.2.6.6
InSysBio is glad to present Cytocon DB 1.2.6.6! Cytocon DB team has reviewed 39 articles to introduce new data. It should be outlined that the total number of concentrations within the Database has already exceeded 10 thousand!
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20 Aug 2020 17:18
InSysBio to present the new version of Immune Response Template
IRT 3.2.0 acquires new models and extended annotations
(Moscow – 20.08.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, presents the new version of its Immune Response Template (IRT). IRT is an efficient and useful tool to boost and facilitate the development of QSP models in immunology and immuno-oncology therapeutic areas. By this point IRT has been developed into a fully-fledged database but InSysBio constantly goes further in its software advancement.
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