The new article “Revolutionizing drug discovery: Integrating artificial intelligence with quantitative systems pharmacology” by Igor Goryanin, Irina Goryanin, Oleg Demin was published in Drug Discovery Today on August 6, 2025.
Oleg Demin, Chief Scientific Advisor and co-founder of InSysBio, highlights, "AI is a hot topic now. QSP was “on hype” previously but now is (almost) routinely applied in drug development. In the paper we are discussing possible ways of their combination. We do not know which ideas mentioned in our paper will be implemented in current QSP framework and how they are able to modify/improve/simplify an application of QSP models. But we think that attempts to implement the ideas in the real QSP modeling efforts is even more important than participation in the AI vs QSP discussions. I would like to acknowledge Igor Goryanin who is first and key author of the paper for his initiative to write the paper and enourmous efforts and enthusiasm!"
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s cutting-edge QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry and innovative biotech companies. For more information about InSysBio, its solutions and services, visit www.insysbio.com
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03 Jun 2025 20:43
InSysBio to present Integration of Cytocon DB and fIVE DB with Heta for QSP modeling
InSysBio releases an integration of CYTOCON DB and fIVE DB with Heta. Now Heta format is upgraded to allow direct query to databases from the QSP model code without working with database websites.
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18 Jun 2025 18:30
InSysBio to publish the new article in CPT: Pharmacometrics & Systems Pharmacology
The new article “Quantitative Systems Pharmacology Model That Describes Neurofilament Light Dynamics During Alzheimer's Disease Progression” by Polina Maliukova, Tatiana Karelina was published in CPT: Pharmacometrics & Systems Pharmacology Journal on June 17, 2025
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25 Jun 2025 14:32
The project aims at translational mechanistic modeling of antibodies to predict human pharmacokinetics and target occupancy in cerebrospinal fluid
InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the extension of collaboration with discoveric bio alpha, a biotechnology company taking next generation antibody technologies into Alzheimer’s Disease.
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