The new article "Quantitative systems pharmacology model of α-synuclein pathology in Parkinson's disease-like mouse for investigation of passive immunotherapy mechanisms" by Olga Ivanova and Tatiana Karelina was published in PSPJournal at the end of August 2024.
Olga Ivanova comments on the article, "Our model of PD-like pathology in mice captures the complex dynamics of αSyn metabolism throughout the brain and the influence of neuroinflammation on PD pathogenesis and dopaminergic neurodegeneration. The model simulations predict how different proposed mechanisms of anti-αSyn immunotherapy may contribute to pathology reduction and how anti-inflammatory therapy may enhance the effect of immunotherapy."
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com
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17 Feb 2022 15:58
InSysBio to present its poster at Tau2022 Global Conference
InSysBio announces its participation in Tau2022 Global Conference. Tau2022 is held virtually on February 22-23, 2022. InSysBio team presents a poster within its frames
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24 Feb 2022 15:27
InSysBio to participate in ASCPT 2022
InSysBio announces its participation in ASCPT 2022 Annual Meeting which is to be held virtually March 16-18, 2022. InSysBio is going to give a talk in frames of its Micro-Theater Session with live Q&A which is scheduled for 3:30 PM ET, Thursday, March 17th. InSysBio team will also present two posters
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