The new article "Quantitative systems pharmacology model of α-synuclein pathology in Parkinson's disease-like mouse for investigation of passive immunotherapy mechanisms" by Olga Ivanova and Tatiana Karelina was published in PSPJournal at the end of August 2024.
Olga Ivanova comments on the article, "Our model of PD-like pathology in mice captures the complex dynamics of αSyn metabolism throughout the brain and the influence of neuroinflammation on PD pathogenesis and dopaminergic neurodegeneration. The model simulations predict how different proposed mechanisms of anti-αSyn immunotherapy may contribute to pathology reduction and how anti-inflammatory therapy may enhance the effect of immunotherapy."
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com
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10 Nov 2021 20:48
InSysBio to take part in ACoP12
InSysBio announces its participation in Twelfth American Conference on Pharmacometrics (ACoP12) which is to be held in virtual format this year from November 8-12, 2021. The theme of ACoP12 is “Charting the Course for Our Future”. InSysBio team is going to present the update at its Virtual Booth and 12 posters in frames of the Conference
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30 Nov 2021 15:17
The new website represents InSysBio’s diverse expertise and corporate philosophy
InSysBio announces the launch of its new website. The aim of redesign was to fully represent all InSysBio’s diversified experience and to reflect the company’s current trend. The new website is more structured, user-friendly and provides more opportunities for feedback.
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