The new article "Quantitative systems pharmacology model of α-synuclein pathology in Parkinson's disease-like mouse for investigation of passive immunotherapy mechanisms" by Olga Ivanova and Tatiana Karelina was published in PSPJournal at the end of August 2024.
Olga Ivanova comments on the article, "Our model of PD-like pathology in mice captures the complex dynamics of αSyn metabolism throughout the brain and the influence of neuroinflammation on PD pathogenesis and dopaminergic neurodegeneration. The model simulations predict how different proposed mechanisms of anti-αSyn immunotherapy may contribute to pathology reduction and how anti-inflammatory therapy may enhance the effect of immunotherapy."
About InSysBio
InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com
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06 Oct 2021 14:56
InSysBio to start the lectures at Lomonosov Moscow State University
InSysBio expert modeler Tatiana Karelina will give the lectures on QSP modeling for the Master's degree students at the Faculty of Physics, Lomonosov Moscow State University.
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12 Oct 2021 10:58
InSysBio to start its annual course at Lomonosov Moscow State University
This year InSysBio CEO Oleg Demin and Head of IRT team Veronika Musatova are giving the course "Mathematical modeling in systems biology and biomedicine" at the Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University.
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