October 1, 2018
InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP), modeling and simulation for drug development, announced today an extension of a collaboration with MedImmune, the global biologics research and development arm of AstraZeneca, for QSP modeling in systemic lupus erythematosus (SLE). The goal is to support the clinical development of anifrolumab, an investigational monoclonal antibody against the type I interferon receptor, by modeling the contributions of key cell types involved in the pathophysiology of lupus that are associated with the type I interferon dysregulation commonly seen with the disease.
“InSysBio’s QSP modeling approach helps us not only to identify predictive biomarkers and means of stratifying patients but also to understand how these biomarkers are related to anifrolmab’s mechanism of action,” said Wendy White, Scientific Director, MedImmune.
“This project is another example of the usefulness of QSP modeling not only in early stages of drug development but also in late stages,” said Oleg Demin Jr, Head of Business Development, InSysBio.
About InSysBio
InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit http://insysbio.com.
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04 Apr 2022 11:02
InSysBio to participate in Quantitative Systems Pharmacology for Immuno-Oncology
InSysBio announces its participation in Quantitative Systems Pharmacology for Immuno-Oncology, a joint meeting of the EMBL's European Bioinformatics Institute (EMBL-EBI) & the UK QSP Network which is to be held 25th & 26th April 2022 in person at the EMBL-EBI Main Building, Hinxton, Cambridgeshire, UK
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25 Apr 2022 17:43
InSysBio's ASCPT 2022 Micro-Theater Session on YouTube
InSysBio has published the videos of its presentation in frames of Micro-Theater Session at ASCPT 2022 Annual Meeting on InSysBio YouTube channel. Oleg Demin and Alexander Stepanov covered the topic of Online databases collecting and processing publicly available data that can help in calibration and validation of QSP models.
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