February 28, 2019
20-22 February 2019 InSysBio company held the 12th Annual Internal Scientific Meeting. Results of the last year and plans for the ongoing year were discussed.
InSysBio launched its first consortium: Alzheimer’s Disease (AD) Modeling Consortium focused on the development of the QSP platform of AD. InSysBio completed four long-term QSP projects in collaboration with three pharmaceutical companies in areas of autoimmune, inflammatory and pulmonary diseases. The online version of Immune Response Template (IRT), a platform for QSP modeling in immunology and immuno-oncology, was launched. Two leading pharmaceutical companies became new users of IRT.
InSysBio modelers have published two research papers in PLOS One and Applied Biochemistry and Biotechnology journals, have read the course on mathematical modeling in systems biology and biomedicine in Lomonosov Moscow State University and have presented in such conferences as ASCPT 2018, PAGE 2018, AAIC 2018, ACoP 9, AAT-AD/PD Focus Meeting, ICSB 2018, Russian National Congress «Man and Drug» and BiotechClub 2018.
In 2019 along with IRT and the AD QSP platform update InSysBio is planning to publish the initial results of the developed PBPK model of antibodies, continue to develop QSP models of various therapies in immuno-oncology (CAR-T, bispecific T-cell engaging antibodies, checkpoint inhibitors) as well as develop QSP platform of hematopoiesis and drug-induced hematologic disorders. InSysBio will participate in AACR Annual Meeting 2019, 15th Annual PEGS Summit, PAGE 2019, ACoP 10 and other conferences.
About InSysBio
InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative approach has already become a part of the drug development process implemented by our strategic partners: nowadays there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. The company has published multiple scientific studies in various therapeutic areas. InSysBio team is developing software and tools for QSP and continuously improves methods for biological modeling. For more information about InSysBio, its solutions and services, visit insysbio.com.
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18 Nov 2019 19:58
Course “Modeling for systems biology and biomedicine” at the Faculty of Bioengineering and Bioinformatics
This year InSysBio CEO Dr Oleg Demin with expert modelers Tatiana Karelina and Evgeny Metelkin and modelers Dmitry Shchelokov, Svetlana Rubina and Veronika Musatova are giving the course “Modeling for systems biology and biomedicine” at the Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University.
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25 Nov 2019 18:47
PK/RO simulator for anti-PD-1 mAbs
InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP), modeling and simulation for drug development, announced the launch of application ‘PK/RO simulator for anti-PD-1 mAbs’. The application is based on the model allowing to predict pharmacokinetics and target binding in human for therapeutic antibodies against PD-1 receptor.
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