InSysBio at QSPC2022

InSysBio to take part in QSPC2022

2 1. 02 Jun 2020 13:24 InSysBio to announce the launch of QSP model of COVID-19 The new open source project to be developed and updated Online InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the launch of its fundamentally new project in response to the ongoing global threat, the open source QSP model of COVID-19. In accordance with its mission, which is to assist pharmaceutical industry to speed up the delivery of the cure to patients, InSysBio team could not stay aside. Thus, the aim of the new project is to develop QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

5 1. 05 Jun 2020 15:04 InSysBio to present IRT Navigator 3 InSysBio presents IRT Navigator 3 which is an application software providing intuitive interface to work with the Immune Response Template Database in accordance with the user’s needs. It supplies the navigation within the schemes and components and efficient development of QSP models based on IRT Database.

8 1. 08 Jun 2020 15:30 InSysBio to perform the first step in development of COVID-19 QSP model InSysBio has performed the first step in the direction of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

12 1. 12 Jun 2020 16:45 InSysBio to release the new version of Cytocon DB 1.1.6.4 We are glad to announce the release of the new version of Cytocon DB 1.1.6.4. The DB was significantly extended with new data due to well-coordinated workflow of Cytocon DB team and its new members. Namely, 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced.

17 1. 17 Jun 2020 15:48 InSysBio to welcome its new team member Dr. Neil Benson InSysBio announces the appointment of Dr. Neil Benson as Principal Consultant in area of business development (Edinburgh-Moscow-16.06.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, is proud to announce its new team member Dr. Neil Benson! Dr. Benson has joined InSysBio as Principal Consultant in area of business development of both INSYSBIO LLC and INSYSBIO UK LIMITED. In his capacity as Principal Consultant to InSysBio, he will support further development of the outstanding IO and AD QSP offering of the company.

22 1. 22 Jun 2020 17:04 InSysBio team posters to be presented at AACR Virtual Annual Meeting II AACR Virtual Annual Meeting II has begun! American Association for Cancer Research Annual Meeting is held virtually this year on June 22-24 due to COVID-19 spread. Today InSysBio team's posters were published on AACR website

30 1. 30 Jun 2020 15:45 InSysBio to present COVID-19 QSP model further development InSysBio continues to move forward in COVID-19 QSP model development. Its aim is to describe virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

events

Conference

March 29, 2022

March, 24

InSysBio announces its participation in Quantitative Systems Pharmacology Conference 2022 (QSPC2022) which is to be held on April 20-22, 2022, Leiden, The Netherlands. InSysBio team is going to present its QSP tools at the Booth and 15 posters in frames of the Conference, namely:

"Stimulation of erythropoiesis with ESA or blood donation: QSP model" by Alexander Stepanov, Galina Lebedeva
"fIVE Database is a repository of in vitro data and estimates of kinetic parameters for systems modeling" by Alexander Stepanov, Veronika Musatova, Anna Victorenko, Ekaterina Goryacheva, Nail Gizzatkulov, Oleg Demin
"CYTOCON DB as a tool to store and analyze in vivo human concentrations of cells and molecules" by Ekaterina Mogilevskaia, Vladislav Leonov, Elita Gerasimuk, Nikolay Pervushin, Nail Gizzatkulov, Oleg Demin
"QSP model that describes neurofilament L protein dynamics in Alzheimer’s disease" by Polina Pchelintseva
"Application of Immune Response Template (IRT) to the COVID19 QSP platform prototype development" by Veronika Musatova, Oleg Demin, Anna Viktorenko, Anastasia Ivanova
"Prediction of pharmacokinetics and optimal dose for a bispecific antibody against CD40 and PD1" by Alexandra Diakonova, Oleg Demin Jr, Dmitry Shchelokov, Oleg Demin
"Collection of methodological findings for QSP model development" by Oleg Demin, Maria Mironovich, Julia Sergienko
"Method to describe multiple effects of regulatory molecules on cell dynamics process in QSP models of immune response" by Oleg Demin, Sergey Smirnov, Galina Lebedeva
"Exploration of structural differences between mechanism-based PK/PD and QSP models" by Oleg Demin
"Comparison Of Different Approaches To Generate Virtual Patient Populations Of Different Sizes For QSP Model Of Erythropoiesis" by Galina Kolesova, Oleg Demin
"Exploration of potential efficacy of tau-targeting immunotherapy and simulation of combination of immunotherapies targeting tau and amyloid using QSP approach" by Tatiana Karelina, Polina Pchelintseva, Oleg Demin
"Confidence Intervals by Constrained Optimization – a Single Algorithm for Identifiability and Predictability Analysis in Systems Biology" by Ivan Borosov, Evgeny Metelkin
"Dynamic and reproducible reports for QSP modeling in R and Julia: working examples" by Evgeny Metelkin, Ivan Borisov
"QSP Modeling of Thrombopoiesis and Essential Thrombocythemia Treatment" by Svetlana Rubina¹, Artem Ivanov², Galina Lebedeva¹

Affiliation: (1) InSysBio, Moscow, Russia, (2) Lomonosov Moscow State University, Moscow, Russia

"QSP model of human granulopoiesis and neutrophil homeostasis under growth factor, stem-cell mobilizing and cytotoxic therapies" by Galina Lebedeva, Alexander Stepanov

See our latest posters: InSysBio team posters

About InSysBio

InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com.

←	June 2020	→
Mo	Tu	We	Th	Fr	Sa	Su
1	2 1. 02 Jun 2020 13:24 InSysBio to announce the launch of QSP model of COVID-19 The new open source project to be developed and updated Online InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the launch of its fundamentally new project in response to the ongoing global threat, the open source QSP model of COVID-19. In accordance with its mission, which is to assist pharmaceutical industry to speed up the delivery of the cure to patients, InSysBio team could not stay aside. Thus, the aim of the new project is to develop QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.	3	4	5 1. 05 Jun 2020 15:04 InSysBio to present IRT Navigator 3 InSysBio presents IRT Navigator 3 which is an application software providing intuitive interface to work with the Immune Response Template Database in accordance with the user’s needs. It supplies the navigation within the schemes and components and efficient development of QSP models based on IRT Database.	6	7
8 1. 08 Jun 2020 15:30 InSysBio to perform the first step in development of COVID-19 QSP model InSysBio has performed the first step in the direction of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.	9	10	11	12 1. 12 Jun 2020 16:45 InSysBio to release the new version of Cytocon DB 1.1.6.4 We are glad to announce the release of the new version of Cytocon DB 1.1.6.4. The DB was significantly extended with new data due to well-coordinated workflow of Cytocon DB team and its new members. Namely, 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced.	13	14
15	16	17 1. 17 Jun 2020 15:48 InSysBio to welcome its new team member Dr. Neil Benson InSysBio announces the appointment of Dr. Neil Benson as Principal Consultant in area of business development (Edinburgh-Moscow-16.06.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, is proud to announce its new team member Dr. Neil Benson! Dr. Benson has joined InSysBio as Principal Consultant in area of business development of both INSYSBIO LLC and INSYSBIO UK LIMITED. In his capacity as Principal Consultant to InSysBio, he will support further development of the outstanding IO and AD QSP offering of the company.	18	19	20	21
22 1. 22 Jun 2020 17:04 InSysBio team posters to be presented at AACR Virtual Annual Meeting II AACR Virtual Annual Meeting II has begun! American Association for Cancer Research Annual Meeting is held virtually this year on June 22-24 due to COVID-19 spread. Today InSysBio team's posters were published on AACR website	23	24	25	26	27	28
29	30 1. 30 Jun 2020 15:45 InSysBio to present COVID-19 QSP model further development InSysBio continues to move forward in COVID-19 QSP model development. Its aim is to describe virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

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