InSysBio to take part in ACoP12

2 1. 02 Jun 2020 13:24 InSysBio to announce the launch of QSP model of COVID-19 The new open source project to be developed and updated Online InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the launch of its fundamentally new project in response to the ongoing global threat, the open source QSP model of COVID-19. In accordance with its mission, which is to assist pharmaceutical industry to speed up the delivery of the cure to patients, InSysBio team could not stay aside. Thus, the aim of the new project is to develop QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

5 1. 05 Jun 2020 15:04 InSysBio to present IRT Navigator 3 InSysBio presents IRT Navigator 3 which is an application software providing intuitive interface to work with the Immune Response Template Database in accordance with the user’s needs. It supplies the navigation within the schemes and components and efficient development of QSP models based on IRT Database.

8 1. 08 Jun 2020 15:30 InSysBio to perform the first step in development of COVID-19 QSP model InSysBio has performed the first step in the direction of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

12 1. 12 Jun 2020 16:45 InSysBio to release the new version of Cytocon DB 1.1.6.4 We are glad to announce the release of the new version of Cytocon DB 1.1.6.4. The DB was significantly extended with new data due to well-coordinated workflow of Cytocon DB team and its new members. Namely, 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced.

17 1. 17 Jun 2020 15:48 InSysBio to welcome its new team member Dr. Neil Benson InSysBio announces the appointment of Dr. Neil Benson as Principal Consultant in area of business development (Edinburgh-Moscow-16.06.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, is proud to announce its new team member Dr. Neil Benson! Dr. Benson has joined InSysBio as Principal Consultant in area of business development of both INSYSBIO LLC and INSYSBIO UK LIMITED. In his capacity as Principal Consultant to InSysBio, he will support further development of the outstanding IO and AD QSP offering of the company.

22 1. 22 Jun 2020 17:04 InSysBio team posters to be presented at AACR Virtual Annual Meeting II AACR Virtual Annual Meeting II has begun! American Association for Cancer Research Annual Meeting is held virtually this year on June 22-24 due to COVID-19 spread. Today InSysBio team's posters were published on AACR website

30 1. 30 Jun 2020 15:45 InSysBio to present COVID-19 QSP model further development InSysBio continues to move forward in COVID-19 QSP model development. Its aim is to describe virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

events

Conference

November 10, 2021

October 27, 2021

InSysBio announces its participation in Twelfth American Conference on Pharmacometrics (ACoP12) which is to be held in virtual format this year from November 8-12, 2021. The theme of ACoP12 is “Charting the Course for Our Future”. InSysBio team is going to present the update at its Virtual Booth and 12 posters in frames of the Conference, namely:

Tuesday, November 9:

Poster Session IA (8:00 - 8:45am AND 12:00 - 12:45pm EST)

PIA-010 "Heta language: Modularity and Reusability in QSP modeling platforms" by Evgeny Metelkin
PIA-014 "Comparison Of Different Approaches To Generate Virtual Patient Populations Of Different Sizes For QSP Model Of Erythropoiesis" by Galina Kolesova
PIA-023 "The QSP model of amyloid beta and tau oligomers influence on synaptic plasticity" by Stepan Lerner

Poster Session IB (8:45 - 9:30am AND 12:45 - 1:30pm EST)

PIB-013 "Quantitative systems pharmacology model for neurofilament L dynamics in Alzheimer's disease pathology" by Polina Pchelintseva, Tatiana Karelina
PIB-018 "PBPK/RO modeling of anti-PDL1 antibodies" by Antonina Nikitich, Oleg Demin Jr

Wednesday, November 10:

Poster Session IIA (8:00 - 8:45am AND 12:00 - 12:45pm EST)

PIIA-018 "Development of QSP model of COVID-19 based on Immune Response Template" by Veronika Musatova, Oleg Demin

Poster Session IIB (8:45 - 9:30am AND 12:45 - 1:30pm EST)

PIIB-006 "PBPK modeling of T cell distribution in cancer patients" by Dmitry Shchelokov¹, Oleg Demin Jr¹, Sara Brett² , Stefan Zajic³, Lourdes Cucurull-Sanchez²

Affiliation: ¹ InSysBio, Moscow, Russia; ² GlaxoSmithKline, Stevenage, Hertfordshire, UK; ³GlaxoSmithKline, Upper Providence, PA, USA

PIIB-031 "Investigation of inflammation during Alzheimer's disease by quantitative systems pharmacology model" by Tatiana Karelina

Thursday, November 11:

Poster Session IIIA (8:00 - 8:45am AND 12:00 - 12:30pm EST)

PIIIA-012 "Application of CYTOCON DB to compare cell/cytokine profile of patients with melanoma, NSCLC, and healthy subjects" by Vladislav Leonov
PIIIA-019 "A Quantitative Systems Pharmacology Model of adverse effects of PI3K? inhibitors on intestine inflammation" by Sergey Smirnov¹, Oleg Demin¹, Erqian Yu², Xiaomin Song², Sri Sahasranaman², Yan Ren²

Affiliation: ¹ InSysBio, Moscow, Russia; ² BeiGene, Beijing, China

Poster Session IIIB (8:45 - 9:30am AND 12:30 - 1:00pm EST)

PIIIB-013 "Semi-mechanistic PK/PD modeling of anti-CD47 therapeutic agent" by Elena Vasileva, Oleg Demin Jr
PIIIB-022 "HetaSimulator is an Open Source Simulation and Parameter Estimation Software for QSP Modeling" by Ivan Borisov, Evgeny Metelkin

Visit our Virtual Booth and follow our presenters!

About InSysBio

InSysBio is a Quantitative Systems Pharmacology (QSP) company located in Moscow, Russia (INSYSBIO LLC) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio’s innovative QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. For more information about InSysBio, its solutions and services, visit www.insysbio.com.

←	June 2020	→
Mo	Tu	We	Th	Fr	Sa	Su
1	2 1. 02 Jun 2020 13:24 InSysBio to announce the launch of QSP model of COVID-19 The new open source project to be developed and updated Online InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the launch of its fundamentally new project in response to the ongoing global threat, the open source QSP model of COVID-19. In accordance with its mission, which is to assist pharmaceutical industry to speed up the delivery of the cure to patients, InSysBio team could not stay aside. Thus, the aim of the new project is to develop QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.	3	4	5 1. 05 Jun 2020 15:04 InSysBio to present IRT Navigator 3 InSysBio presents IRT Navigator 3 which is an application software providing intuitive interface to work with the Immune Response Template Database in accordance with the user’s needs. It supplies the navigation within the schemes and components and efficient development of QSP models based on IRT Database.	6	7
8 1. 08 Jun 2020 15:30 InSysBio to perform the first step in development of COVID-19 QSP model InSysBio has performed the first step in the direction of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.	9	10	11	12 1. 12 Jun 2020 16:45 InSysBio to release the new version of Cytocon DB 1.1.6.4 We are glad to announce the release of the new version of Cytocon DB 1.1.6.4. The DB was significantly extended with new data due to well-coordinated workflow of Cytocon DB team and its new members. Namely, 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced.	13	14
15	16	17 1. 17 Jun 2020 15:48 InSysBio to welcome its new team member Dr. Neil Benson InSysBio announces the appointment of Dr. Neil Benson as Principal Consultant in area of business development (Edinburgh-Moscow-16.06.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, is proud to announce its new team member Dr. Neil Benson! Dr. Benson has joined InSysBio as Principal Consultant in area of business development of both INSYSBIO LLC and INSYSBIO UK LIMITED. In his capacity as Principal Consultant to InSysBio, he will support further development of the outstanding IO and AD QSP offering of the company.	18	19	20	21
22 1. 22 Jun 2020 17:04 InSysBio team posters to be presented at AACR Virtual Annual Meeting II AACR Virtual Annual Meeting II has begun! American Association for Cancer Research Annual Meeting is held virtually this year on June 22-24 due to COVID-19 spread. Today InSysBio team's posters were published on AACR website	23	24	25	26	27	28
29	30 1. 30 Jun 2020 15:45 InSysBio to present COVID-19 QSP model further development InSysBio continues to move forward in COVID-19 QSP model development. Its aim is to describe virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.

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