InSysBio to present at AAIC 2018

November 2018

6 1. 06 Nov 2018 17:27 Investigation of amyloid pathology mechanisms and prediction of clinical trial results using QSP model InSysBio presents the video of Tatiana Karelina’s talk in framework of session “From translational PKPD models to quantitative system pharmacology in neurodegeneration drug development” at the 9th American Conference on Pharmacometrics (ACoP9):

26 1. 26 Nov 2018 14:03 InSysBio updates Immune Response Template online InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP) modeling and simulation for drug development, today announced a release of updated version of Immune Response Template (IRT) online. The main update in new 2.1.0 version is myeloid-derived suppressor cells (MDSCs). Published human in vitro and in vivo data were analyzed to reconstruct monocytic MDSCs (Mo-MDSCs) and granulocytic MDSCs (Gr-MDSCs) life cycles, derive equations and identify parameters.

events

Conference

July 17, 2018

July 17, 2018

InSysBio announces their participation at Alzheimer’s Association International Conference (AAIC) 2018 being held July 22-26 in Chicago, IL. InSysBio welcomes visitors at the booth #630. InSysBio will present two posters:

Sunday, July 22:

P1-122: “Translational quantitative systems pharmacology model of tauopathies” by Tatiana Karelina and Alexander Stepanov

Monday, July 23:

P2-147: “Description of different amyloid toxic species and pathology progression by mechanistic quantitative systems pharmacology model” by Tatiana Karelina, Alexander Stepanov and Alena Zhukova

About InSysBio

INSYSBIO LLC was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of quantitative systems pharmacology (QSP) modeling. InSysBio’s innovative approach has already become a part of the drug development process implemented by our strategic partners: nowadays there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry. The company has published multiple scientific studies in various therapeutic areas. InSysBio team is developing software and tools for QSP and continuously improves methods for biological modeling. For more information about InSysBio, its solutions and services, visit www.insysbio.com

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5	6 1. 06 Nov 2018 17:27 Investigation of amyloid pathology mechanisms and prediction of clinical trial results using QSP model InSysBio presents the video of Tatiana Karelina’s talk in framework of session “From translational PKPD models to quantitative system pharmacology in neurodegeneration drug development” at the 9th American Conference on Pharmacometrics (ACoP9):	7	8	9	10	11
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26 1. 26 Nov 2018 14:03 InSysBio updates Immune Response Template online InSysBio, a pioneer in Quantitative Systems Pharmacology (QSP) modeling and simulation for drug development, today announced a release of updated version of Immune Response Template (IRT) online. The main update in new 2.1.0 version is myeloid-derived suppressor cells (MDSCs). Published human in vitro and in vivo data were analyzed to reconstruct monocytic MDSCs (Mo-MDSCs) and granulocytic MDSCs (Gr-MDSCs) life cycles, derive equations and identify parameters.	27	28	29	30

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