From Literature to Model-Ready Data: Cutting Weeks Off Your QSP Workflow

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April 15, 2026

InSysBio announces the upcoming webinar on the New Data Annotation Service for CYTOCON DB & fIVE DB on May 19, 2026, 16:00 CEST / 10:00 ET (Microsoft Teams).

Stop mining PubMed. Start modeling.

Before the first equation is written, QSP modelers face a data problem. Sourcing reliable baseline concentrations, extracting kinetic parameters from in vitro studies, standardizing units across dozens of papers, deciding which values to trust — this work typically consumes 4–8 weeks per project, delays model development, and inflates costs.

InSysBio has built two purpose-designed databases to address this bottleneck.

CYTOCON DB is a manually curated database of human in vivo cell and cytokine concentrations: 551 disease types, 253 tissues, 813 molecules, 301 cell types, and over 112,000 standardized data points extracted from nearly 3,000 published sources. Content grows by approximately 1,500 values per month.

fIVE DB captures quantitative parameters derived from in vitro and ex vivo experiments on cell processes — secretion, proliferation, cell death, migration, differentiation, and cytokine degradation — with over 43,000 parameters extracted from 2,247 sources, pre-processed into forms directly usable in mathematical models.

For projects requiring data beyond existing database coverage — rare indications, novel targets, or expanded parameter sets — InSysBio's Data Annotation Service delivers custom, expert-curated datasets within 30 days.

This webinar walks through what each database contains, how the data maps to QSP calibration and virtual patient workflows, and when custom annotation fills the gaps.

WHAT YOU'LL LEARN

  • Why manual literature curation remains the biggest time sink in QSP projects and what it actually costs
  • What CYTOCON DB and fIVE DB contain, how they're organized, and how they're updated
  • How standardized database outputs connect to model calibration and virtual patient generation
  • When and how InSysBio's Data Annotation Service complements database coverage for bespoke projects

Speaker: Vladislav Leonov, CYTOCON DB and fIVE DB Manager.

REGISTER HERE

About InSysBio

InSysBio is a group of Quantitative Systems Pharmacology (QSP) companies located in Limassol, Cyprus (INSYSBIO CY Ltd) and Edinburgh, UK (INSYSBIO UK LIMITED). InSysBio was founded in 2004 and has an extensive track record of helping pharmaceutical companies to make right decisions on the critical stages of drug research and development by application of QSP modeling. InSysBio's cutting-edge QSP approach has already become a part of the drug development process implemented by our strategic partners: there are more than 100 completed projects in collaboration with leaders of pharmaceutical industry and innovative biotech companies. For more information about InSysBio, its solutions and services, visit www.insysbio.com

June 2020
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1. 02 Jun 2020 13:24 InSysBio to announce the launch of QSP model of COVID-19 The new open source project to be developed and updated Online InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, announces the launch of its fundamentally new project in response to the ongoing global threat, the open source QSP model of COVID-19. In accordance with its mission, which is to assist pharmaceutical industry to speed up the delivery of the cure to patients, InSysBio team could not stay aside. Thus, the aim of the new project is to develop QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.
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1. 05 Jun 2020 15:04 InSysBio to present IRT Navigator 3 InSysBio presents IRT Navigator 3 which is an application software providing intuitive interface to work with the Immune Response Template Database in accordance with the user’s needs. It supplies the navigation within the schemes and components and efficient development of QSP models based on IRT Database.
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1. 08 Jun 2020 15:30 InSysBio to perform the first step in development of COVID-19 QSP model InSysBio has performed the first step in the direction of development of QSP model of COVID-19 describing virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.
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1. 12 Jun 2020 16:45 InSysBio to release the new version of Cytocon DB 1.1.6.4 We are glad to announce the release of the new version of Cytocon DB 1.1.6.4. The DB was significantly extended with new data due to well-coordinated workflow of Cytocon DB team and its new members. Namely, 54 diseases, 24 tissues, 42 molecules, 24 cells and 3701 concentrations were introduced.
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1. 17 Jun 2020 15:48 InSysBio to welcome its new team member Dr. Neil Benson InSysBio announces the appointment of Dr. Neil Benson as Principal Consultant in area of business development (Edinburgh-Moscow-16.06.2020) InSysBio, one of the world’s pioneers of Quantitative Systems Pharmacology (QSP) modeling, is proud to announce its new team member Dr. Neil Benson! Dr. Benson has joined InSysBio as Principal Consultant in area of business development of both INSYSBIO LLC and INSYSBIO UK LIMITED. In his capacity as Principal Consultant to InSysBio, he will support further development of the outstanding IO and AD QSP offering of the company.
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1. 22 Jun 2020 17:04 InSysBio team posters to be presented at AACR Virtual Annual Meeting II AACR Virtual Annual Meeting II has begun! American Association for Cancer Research Annual Meeting is held virtually this year on June 22-24 due to COVID-19 spread. Today InSysBio team's posters were published on AACR website
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1. 30 Jun 2020 15:45 InSysBio to present COVID-19 QSP model further development InSysBio continues to move forward in COVID-19 QSP model development. Its aim is to describe virus and host cell life cycles, innate and adoptive immune response and possible therapeutic treatments.
     
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