Institute for Systems Biology participates in American Society for Clinical Pharmacology and Therapeutics 2017 Meeting

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Conference
March 15, 2017

Moscow, Russia – March 14th, 2017. Institute for Systems Biology Moscow – a company, providing modeling services for innovative drug design, announced participation in ASCPT 2017 Meeting, which is held on 15-18 March in Washington, DC. ISBM will present several studies and demonstrate an updated version of platform for quantitative systems pharmacology modeling of immune response - Immune Response Template (IRT). Also the ISBM CEO Oleg Demin will take part in the Editorial Board Meeting of the CPT: Pharmacometrics & Systems Pharmacology Journal (Nature Publishing Group).

ISBM is honored for such a great opportunity to share the latest results with colleagues and to show its research integrated in commercial project. On ASCPT2017 Meeting the ISBM team will be focused on the QSP-modeling of immune response. They will present mechanistic approaches for description of the different stages of immune cells lifecycle: maturation, migration, activation and more.

All these theoretical methods were used in the updated platform for “rapid” QSP modeling. With the help of IRT one can create model templates of immune response in a few clicks. This can significantly improve the development of drugs, for example in the field of immuno-oncology.

To learn more about the mechanistic modeling of cell dynamics, to talk with the leading specialists of the Institute for Systems Biology Moscow and to see the possibilities of IRT one can by visiting ISBM stand on March 15-18 from 9 am in Exhibit Hall A / B South, Washington Marriott Wardman Park, Washington, DC, USA.

The poster session materials are shared on the company page http://insysbio.ru/en/publication/materials

  • Chemokine Mediated Cell Migration.
  • Cytokine Production by Immune Cells.
  • Effect of Co-Stimulatory and Co-Inhibitory Surface Molecules on Processes Associated with Cell-to-Cell Interactions.
  • Mathematical Description of Multiple Effects of Regulatory Molecules.
  • Neutrophils Survival in the Presence of Pro-Inflammatory Cytokines.
  • Mechanistic Model of Neutrophil Cell Dynamics and Activation to Inform Systems Pharmacology Modeling Of the Immune Response.
  • Mechanistic Model of Mast Cell Life Cycle, Activation and Release of Bioactive Molecules Designed to Support Systems Pharmacology Modeling of the Immune Response.

September 2017
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1. 28 Sep 2017 19:27 Computer model showed an optimal anti-amyloid treatment Moscow, Russia, September 28, 2017. One must activate amyloid degradation as soon as possible to prevent the appearance of the protein plaques in brain under Alzheimer’s conditions. This conclusion was reached by scientists from the biotechnology company InSysBio, who created the first computer model of the disease. The final part of the work has been recently published in CPT: Pharmacometrics & Systems Pharmacology.
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