Journal articles


Karelina T., Demin O., Demin Jr. O., Duvvuri S., Nicholas T. Studying the progression of amyloid pathology and its therapy using translational longitudinal model of accumulation and distribution of amyloid beta. CPT: Pharmacometrics & Systems Pharmacology. 2017. doi: 10.1002/psp4.12211.

Karelina T., Demin O., Nicholas T., Lu Y., Duvvuri S., Barton HA. A translational systems pharmacology model for Aβ kinetics in mouse, monkey, and human. CPT: Pharmacometrics & Systems Pharmacology. 2017. doi: 10.1002/psp4.122116.

Shalgunov V, Zaytseva-Zotova D, Zinchenko A, Levada T, Shilov Y, Andreyev D, Dzhumashev D, Metelkin E, Urusova A, Demin O, McDonnell K, Troiano G, Zale S, Safarovа E. Comprehensive study of the drug delivery properties of poly(l-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice. J Control Release. S0168-3659(17)30646-6.


Karelina T., Voronova V., Demin O., Colice G., Agoram BM. A Mathematical Modeling Approach to Understanding the Effect of Anti-Interleukin Therapy on Eosinophils. CPT: Pharmacometrics & Systems Pharmacology. 2016. v.5(6), p.608-616.

Noren DP., Long BL., Norel R., Rrhissorrakrai K., Hess K., Hu CW., Bisberg AJ., Schultz A., Engquist E., Liu L., Lin X., Chen GM., Xie H., Hunter GAM., Boutros PC., Stepanov O. A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis. PLOS Computational Biology. 2016. v.12(6), e1004890.


Vinogradova S., Zhudenkov K., Benson N., Van Der Graaf P., Demin O., Karelina T. Prediction of long-term treatment outcome in HCV following 24 day PEG-IFN alpha-2b therapy using population pharmacokinetic-pharmacodynamic mixture modeling and classification analysis. Journal of theoretical biology. 2015. v.382, p.91-98.