Journal articles


Karelina T., Lerner S., Stepanov A., Meerson M., Demin O. Monoclonal antibody therapy efficacy can be boosted by combinations with other treatments: predictions using an integrated Alzheimer's Disease Platform. CPT Pharmacometrics Syst Pharmacology. 2021. doi: 10.1002/psp4.12628.


Borisov I., Metelkin E. Confidence intervals by constrained optimization—An algorithm and software package for practical identifiability analysis in systems biology. PLoS Comput Biol 16(12): e1008495.


Stepanov A., Karelina T., Markevich N., Demin O., Nicholas T. A mathematical model of multisite phosphorylation of tau protein. PLOS ONE 13(3): e0194002. doi: 10.1371/journal.pone.0192519.

Smirnov S., Demin O., Torgonskaya M., Firsova Yu., Zhukov V., Zagustina N. Optimization of the Process of Air Purification from Dichloromethane in a Biofilter with an Irrigated Layer by Mathematical Modeling. Appl Biochem Microbiol (2018) 54: 702.


Karelina T., Demin O., Demin Jr. O., Duvvuri S., Nicholas T. Studying the progression of amyloid pathology and its therapy using translational longitudinal model of accumulation and distribution of amyloid beta. CPT: Pharmacometrics & Systems Pharmacology. 2017. doi: 10.1002/psp4.12211.

Karelina T., Demin O., Nicholas T., Lu Y., Duvvuri S., Barton HA. A translational systems pharmacology model for A? kinetics in mouse, monkey, and human. CPT: Pharmacometrics & Systems Pharmacology. 2017. doi: 10.1002/psp4.122116.