2016
ASCPT 2016, San Diego, CA, US
Analysis of brain pharmacodynamics of gamma-secretase inhibitors using quantitative translational systems pharmacology model
Authors: Tatiana Karelina1, Oleg Demin1, Timothy Nicholas2, Sridhar Duvvuri2
Affiliation: 1InSysBio, Moscow, Russia; 2Pfizer Worldwide R&D, Groton, CT, USA
Population modeling study for evaluation of effective and safe dose of RPH-104 for the treatment of Behcet’s syndrome and FMF
Authors: Evgeny Metelkin1, Tatiana Petukhova1, Oleg Demin1, Elena Shipaeva2, Mikhail Samsonov2, Anna Krotkova2, Yan Lavrovsky3
Affiliation: 1InSysBio, Moscow, Russia; 2JSC R-Pharm, Moscow, Russia; 3R-Pharm Overseas, Inc., San Diego, US
Systems Pharmacology Model Of Hepatitis C: Exploration Of Effect Of Combinations Of Direct Antiviral Agents On HCV Production During Treatment Of HCV Patients
Authors: Oleg Demin Jr, Oleg Demin
Population modeling and simulation of RPH-203 effects in the context of prevention of skeletal-related events in patients with bone metastases
Authors: Evgeny Metelkin1, Tatiana Petukhova1, Oleg Demin1, Shorena Archuadze2, Galina Konopleva2, Dmitry Koloda2, Mikhail Samsonov2
Affiliation: 1InSysBio, Moscow, Russia; 2JSC R-Pharm, Moscow, Russia
2015
ASCPT 2015, New Orleans, LA, US
Systems Pharmacology Modeling of Hypomethylating agents Decitabine and SGI-110 for Evaluation of AML treatment by targeting the S-phase with prolonged Pharmacokinetic exposures
Authors: Aram Oganesian, Oleg Demin Jr, Antonina Nikitich, Oleg Demin and Mohammad Azab
Affiliation: Astex Pharmaceuticals Inc., Dublin, CA, US; 2InSysBio, Moscow, Russia
20th Congress of EHA, Vienna, Austria
Application of Systems Pharmacology Modeling for Evaluation of Therapies Effect on Blast Dynamics in Acute Lymphoblastic Leukemia
Authors: Antonina Nikitich, Oleg Demin Jr
2014
Systems Pharmacology in Drug Discovery & Development, Noordwijkerhout, The Netherlands
A systems pharmacology model of purine metabolism to explore novel options for the treatment of Gout
Authors: Pinky Dua, Oleg Demin Jr, Viktor Sokolov, Tatiana Yakovleva, Oleg Demin, Piet van der Graaf
Affiliation: Clinical Pharmacology, Pfizer Neusentis, Cambridge UK; InSysBio, Moscow, Russia; Leiden Academic Centre for Drug Research (LACDR), The Netherland
ASCPT 2014, Atlanta, GE, US
Systems Pharmacology Modeling of Calcium and Phosphate Metabolism in Chronic Kidney Disease
Authors: Antonina Bakhmutova, Oleg Demin Jr, Oleg Demin
Development and Application of Systems Pharmacology Model to Predict Nausea Resulted from Administration GLP-1 Agonists
Authors: Veronika Voronova, Oleg Demin Jr, Sergei Smirnov, Oleg Demin
EMBL-EBI Industry Systems Pharmacology Workshop, Cambridge, UK
Systems pharmacology modeling in drug research and development: application of modeling technique
Speaker: Oleg Demin
First
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