2017
7th German-Russian Week of the Young Researcher, Moscow, Russia
SbmlViewer is a visualization tool for systems biology modeling
Authors: Viktoria Tkachenko, Evgeny Metelkin
AD/PD 2017, Vienna, Austria
Amyloid toxicity and different mechanisms of action for amyloid-targeted treatments studied by quantitative systems pharmacology model
Authors: Tatiana Karelina1, Timothy Nicholas2
Affiliation: 1InSysBio, Moscow, Russia; 2Pfizer Worldwide R&D, Groton, CT, USA
ASCPT 2017, Washington DC, US
Mechanistic model of neutrophil cell dynamics and activation to inform systems pharmacology modeling of the immune response
Authors: Galina Lebedeva, Sergey Smirnov, Evgeny Metelkin, Oleg Demin
Mathematical description of multiple effects of regulatory molecules
Authors: Sergey Smirnov, Evgeny Metelkin, Galina Lebedeva, Oleg Demin
2016
ACoP7, Bellevue, WA, US
Mechanistic approach to describe multiple effects of regulatory molecules on cell dynamics process in immune response
Authors: Oleg Demin, Evgeny Metelkin, Galina Lebedeva, Sergey Smirnov
Quantitative systems pharmacology model of amyloid pathology allows for clinical endpoint prediction and hypothesis testing
Authors: Tatiana Karelina1, Oleg Demin1, Timothy Nicholas2, Sridhar Duvvuri2
Affiliation: 1InSysBio, Moscow, Russia; 2Pfizer Worldwide R&D, Groton, CT, USA
Exploration of differences between mechanism-based PK/PD and systems pharmacology models
Authors: Oleg Demin
Modeling of immune response suppression by hepatitis C virus and nivolumab treatement in chronic hepatitis C patients using quantitative systems pharmacology approach
Authors: Oleg Demin Jr
PAGE 2016, Lisboa, Portugal
Population PK modeling of RPH-104, novel optimized IL-1 beta trap, and assessment of the immunogenicity effect on pharmacokinetics
Authors: Evgeny Metelkin1, Tatiana Petukhova1, Oleg Demin1, Elena Shipaeva2, Mikhail Samsonov2, Anna Krotkova2, Yan Lavrovsky3
Affiliation: 1InSysBio, Moscow, Russia; 2JSC R-Pharm, Moscow, Russia; 3R-Pharm Overseas, Inc., San Diego, US
The International Liver Congress 2016, Barcelona, Spain
Quantitative Systems Pharmacology model of Hepatitis C: Prediction of Results of Ongoing Clinical Trials of Direct Antiviral Agents Combination Therapies
Authors: Oleg Demin Jr
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